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豐華生物科技股份有限公司

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L. rhamnosus F-1

A patented functional strain derived from the healthy female reproductive tract

Lacticaseibacillus. rhamnosus F-1 is a probiotic strain derived from the healthy female reproductive tract. Supported by rigorous scientific studies and multiple patents, this strain demonstrates outstanding potential across specific health areas. Beyond its role in supporting women’s intimate health, F-1 has also shown strong applicability in oral health, gastric comfort, and modulation of inflammatory responses.

Core Areas of Application

The multifunctionality of F-1 enables its integration into a wide range of product formulations, supported by solid scientific evidence:
Women’s Health: Helps maintain vaginal microbiome balance with demonstrated modulation of associated microorganisms.
Oral Care: Patents demonstrate its ability to inhibit oral pathogens, applicable in food and oral hygiene products.
Gastric Comfort: Clinical data support its protective potential against Helicobacter pylori, supporting a healthy gastric environment.
Immune Modulation: Scientific research highlights its capacity to modulate inflammatory responses of epithelial and immune cells.

Functional Applications in PRONULIFE^® Formulations
F-1 has been incorporated into several clinically validated PRONULIFE^® formulations:


Women’s Intimate Health PRONULIFE^® VagProtect	Stomach Health PRONULIFE^® GasProtect / GasProtect-M	Immune & Allergy Support PRONULIFE^® BabyAllieve

Key Patents
Taiwan

I639389: Food and pharmaceutical compositions containing lactic acid bacteria for inhibiting oral pathogens
I784210: Compositions for inhibiting vaginal pathogens and related applications
I792249: Fermented cultures of lactic acid bacteria for supporting protection against Helicobacter pylori

China

CN102835657B: Lactic acid bacteria food compositions with anti-inflammatory and vaginal health-supporting functions
CN108338361B: Food, oral hygiene, and pharmaceutical compositions containing lactic acid bacteria for oral health
CN115137756B: Fermented cultures of lactic acid bacteria for supporting gastric health

📧 Contact us: glac@glac.com.tw

Further Reading:

References:
Potential of probiotics strains to modulate the inflammatory responses of epithelial and immune cells in vitro.