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PRONEX® Probiotics Manufacturing Technology
PRONEX® is an exclusive probiotic manufacturing process developed by Glac Biotech, which has accumulated decades of experience in research and analysis of probiotics through its big data platform. By incorporating modern gene chip technology and developing a highly intelligent control system, Glac has become a leader in the probiotics industry. From research and development to mass production, the company strictly monitors its production processes to ensure compliance with the highest standards of quality control. As a result, Glac Biotech has established itself as an Expert in Probiotics and Postbiotics Integrated Solutions and produces safe, effective, and high-quality probiotic powder raw materials.
Glac Biotech has established an independent strain database and built a proprietary strain‑screening platform to efficiently identify potential functional probiotic genes. We select strains that can withstand strict tests involving up to 7 hours of exposure to gastric acid and bile salts, while also demonstrating strong intestinal adhesion. After third‑party identification and confirmation, we assign Glac‑exclusive strain identity codes. We then proceed with precise strain application studies, conducting in vitro tests and screening to identify strains with superior efficacy across various functional domains.
Glac is a world leader in developing Totipro® Postbiotics and has developed and implemented Heat-Lock Technology (TW M617922). Following an optimized 48-hour fermentation process, the mixed strains undergo precise thermal treatment to inactivate microorganisms while preserving essential fermentation-derived nutrients, which can be immediately utilized to support nutritional needs.

Building Rigorous Experimental Designs to Achieve Research and Validation Goals
Glac Biotech has established an independent strain database and built a proprietary strain‑screening platform to efficiently identify potential functional probiotic genes. We select strains that can withstand strict tests involving up to 7 hours of exposure to gastric acid and bile salts, while also demonstrating strong intestinal adhesion. After third‑party identification and confirmation, we assign Glac‑exclusive strain identity codes. We then proceed with precise strain application studies, conducting in vitro tests and screening to identify strains with superior efficacy across various functional domains.Leading the World with the Highest Standards in Probiotic Production Processes
For potential strains, we utilize fully automated process control equipment within our facilities to eliminate quality variations caused by human factors. We have developed the world’s leading high-density cultivation technology, creating optimal growth and metabolic conditions tailored to each probiotic strain, thereby enhancing production efficiency. All raw materials are delivered through a closed pipeline system, ensuring transparency in every step of the process and minimizing contamination risks. Our facilities are exclusively equipped with the “Intelligent Flash Cooling System,” which encapsulates probiotic cells in microcrystalline spheres, significantly enhancing strain stability and preserving optimal probiotic activity. IPQC (In-Process Quality Control) continuously monitors the entire process, strictly controlling all critical steps to ensure safety, stability, and consistent high quality of probiotic raw materials—empowering our products with the competitiveness to capture early market opportunities.Proprietary Process Technologies: Mastering the Core of Probiotic Manufacturing
Through years of expertise, our R&D center has developed an exclusive encapsulation method for probiotic strains. Our strain encapsulation technology (TW M613340) employs an optimized carbon-to-nitrogen ratio to ensure strain integrity, preserve optimal activity, and significantly enhance product shelf-life stability.Glac is a world leader in developing Totipro® Postbiotics and has developed and implemented Heat-Lock Technology (TW M617922). Following an optimized 48-hour fermentation process, the mixed strains undergo precise thermal treatment to inactivate microorganisms while preserving essential fermentation-derived nutrients, which can be immediately utilized to support nutritional needs.

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