1.The impact of selenium administration on severe sepsis or septic shock: a meta-analysis of randomized controlled trialsLin Kong et al. Afr Health Sci. 2021 Mar.(補硒對嚴重敗血症或敗血性休克的影響:隨機對照試驗的薈萃分析)
薈萃分析中納入了 1482 名患者的 試驗。
結論: 補硒可顯著降低敗血性休克患者的全因死亡率和住院時間
2.Erythrocyte selenium concentration predicts intensive care unit and hospital mortality in patients with septic shock: a prospective observational studyNara Aline Costa et al. Crit Care. 2014.(紅血球硒濃度可預測感染性休克患者的重症監護病房和醫院死亡率:一項前瞻性觀察研究)
結論是紅血球硒濃度是感染性休克患者 ICU 和醫院死亡率的預測因子
3.Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shockMatthias W A Angstwurm et al. Crit Care Med. 2007 Jan.(硒在重症監加護 (SIC) 中的應用:一項針對嚴重全身性發炎反應症候群、敗血症和膿毒性休克患者的前瞻性隨機、安慰劑對照、多中心研究的結果)
結論是高劑量亞硒酸鈉(1000微克)輔助治療可降低嚴重敗血症或感染性休克患者的死亡率。
4.Selenoprotein P, rather than glutathione peroxidase, as a potential marker of septic shock and related syndromesX Forceville et al. Eur Surg Res. 2009.